Anti-citrullinated alpha enolase antibodies, interstitial lung disease and bone erosion in rheumatoid arthritis
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DOI: 10.1093/rheumatology/kex520
Abstract: Objectives RA is an articular chronic inflammatory disease that in a subgroup of patients can also present with extra-articular manifestations (EAMs). Despite intense investigation on this topic, reliable biomarkers for EAMs are lacking. In recent… read more here.
Keywords: disease; anti citrullinated; anti cep; alpha enolase ... See more keywords
The potential significance of alpha‐enolase (ENO1) in lung adenocarcinomas – A utility of the immunohistochemical expression in pathologic diagnosis
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DOI: 10.1111/pin.12607
Abstract: We herein analyzed the relationships among the immunohistochemical expression of alpha‐enolase (ENO1) and clinicopathological factors in order to define the significance of ENO1 in lung adenocarcinomas (ADCs). ENO1 expression was detected in most of the… read more here.
Keywords: enolase eno1; adcs; eno1; expression ... See more keywords
Preclinical Validation of Alpha-Enolase (ENO1) As a Novel Immunometabolic Target in Multiple Myeloma
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DOI: 10.1182/blood-2019-123328
Abstract: Introduction. Bone marrow plasmacytoid dendritic cells (pDCs) in patients with multiple myeloma (MM) both promote tumor growth, survival, and drug resistance, as well as induce decreased T/NK effector cell function and immune suppression. Delineation of… read more here.
Keywords: expression; cell; alpha enolase; eno1 ... See more keywords
Alpha-enolase in viral target cells suppresses the human immunodeficiency virus type 1 integration
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DOI: 10.1186/s12977-020-00539-9
Abstract: Background A protein exhibiting more than one biochemical function is termed a moonlighting protein. Glycolytic enzymes are typical moonlighting proteins, and these enzymes control the infection of various viruses. Previously, we reported that glyceraldehyde 3-phosphate… read more here.
Keywords: integration; hiv; target; alpha enolase ... See more keywords
Alpha-Enolase: Emerging Tumor-Associated Antigen, Cancer Biomarker, and Oncotherapeutic Target
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DOI: 10.3389/fgene.2020.614726
Abstract: Alpha-enolase, also known as enolase-1 (ENO1), is a glycolytic enzyme that “moonlights” as a plasminogen receptor in the cell surface, particularly in tumors, contributing to cancer cell proliferation, migration, invasion, and metastasis. ENO1 also promotes… read more here.
Keywords: cancer; cancer biomarker; alpha enolase; tumor ... See more keywords
Alpha-Enolase (ENO1) Correlates with Invasiveness of Cutaneous Melanoma—An In Vitro and a Clinical Study
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DOI: 10.3390/diagnostics12020254
Abstract: Simple Summary Alpha-enolase (ENO1) undergoes accentuated overexpression in several solid cancers, but little is known about its status in cutaneous melanoma. The aim of this study was to investigate the prognostic significance of ENO1 in… read more here.
Keywords: enolase eno1; cutaneous melanoma; alpha enolase; melanoma ... See more keywords
Over-Expression of Alpha-Enolase as a Prognostic Biomarker in Patients with Pancreatic Cancer
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DOI: 10.7150/ijms.18736
Abstract: Background: Alpha-enolase is an important glycolytic enzyme, and its aberrant expression has been associated with multiple tumor progression. However, few studies investigated the expression of alpha-enolase and its clinical significance in pancreatic cancer (PC). Objectives:… read more here.
Keywords: expression alpha; expression; pancreatic cancer; alpha enolase ... See more keywords