Effect of nicotine and alpha‐7 nicotinic modulators on visceral pain‐induced conditioned place aversion in mice
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pain"
DOI: 10.1002/ejp.1231
Abstract: Preclinical assays of affective and sensorial aspects of nociception play a key role in research on both the neurobiology of pain and the development of novel analgesics. Therefore, we investigated the effects of nicotine and… read more here.
Keywords: nicotine alpha; effect nicotine; visceral pain; alpha nicotinic ... See more keywords
GW29-e1791 Nicotine promotes atherosclerosis development in apolipoprotein E-deficient mice through alpha 1 nicotinic acetylcholine receptor on RAW264.7 and MOVAS cells
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American College of Cardiology"
DOI: 10.1016/j.jacc.2018.08.217
Abstract: In our study, we investigated whether nicotine promotes the development of atherosclerosis throughout alpha 1 nicotinic acetylcholine receptor in apolipoprotein E-deficient mice .In vitro, we investigated whether the migration and proliferation of VSMC and macrophage… read more here.
Keywords: alpha nicotinic; nicotinic acetylcholine; apolipoprotein deficient; nicotine promotes ... See more keywords
Abstract 4203: Alpha 9 nicotinic acetylcholine receptor promotes tumor progression in triple negative breast cancer
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-4203
Abstract: Purpose: To assess the potential therapeutic target on the alpha 9 nicotinic acetylcholine receptor (α9-nAChR) and the insulin-like growth factor (IGF)-I receptor (IGF-IR) for preventing distant metastasis in TNBC patients. Experimental Design: Expression levels of… read more here.
Keywords: alpha nicotinic; nicotinic acetylcholine; igf; cancer ... See more keywords
Alpha 7 nicotinic receptors attenuate neurite development through calcium activation of calpain at the growth cone
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0197247
Abstract: The α7 nicotinic acetylcholine receptor (nAChR) is a ligand-gated ion channel that plays an important role in cellular calcium signaling contributing to synaptic development and plasticity, and is a key drug target for the treatment… read more here.
Keywords: calpain; alpha nicotinic; activation; calcium ... See more keywords
The Alpha 7 Nicotinic Acetylcholine Receptor Does Not Affect Neonatal Brain Injury
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10082023
Abstract: Inflammation plays a central role in the development of neonatal brain injury. The alpha 7 nicotinic acetylcholine receptor (α7nAChR) can modulate inflammation and has shown promising results as a treatment target in rodent models of… read more here.
Keywords: brain; nicotinic acetylcholine; alpha nicotinic; neonatal brain ... See more keywords
The Protective Effect of Alpha 7 Nicotinic Acetylcholine Receptor Activation on Critical Illness and Its Mechanism
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DOI: 10.7150/ijbs.16404
Abstract: Critical illnesses and injuries are recognized as major threats to human health, and they are usually accompanied by uncontrolled inflammation and dysfunction of immune response. The alpha 7 nicotinic acetylcholine receptor (α7nAchR), which is a… read more here.
Keywords: receptor; acetylcholine receptor; alpha nicotinic; nicotinic acetylcholine ... See more keywords