The risk of dementia with the use of 5 alpha reductase inhibitors
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the Neurological Sciences"
DOI: 10.1016/j.jns.2017.05.064
Abstract: INTRODUCTION There has been considerable interest in the interplay between testosterone and cognition. Dihydrotestosterone (DHT), which has been correlated with cognitive function, is significantly reduced with the use of 5 alpha reductase inhibitors (5ARI) for… read more here.
Keywords: risk dementia; use; dementia; alpha reductase ... See more keywords
May patients receiving 5-alpha-reductase inhibitors be in higher risk of COVID-19 complications?
Sign Up to like & getrecommendations! Published in 2020 at "Medical Hypotheses"
DOI: 10.1016/j.mehy.2020.109751
Abstract: Abstract COVID-19 pandemic is a major challenge for global and national healthcare providers. Number of new cases is continuously increasing with an emerging trend showing worse prognosis in males in comparison to females. Based on… read more here.
Keywords: may patients; alpha reductase; patients receiving; receiving alpha ... See more keywords
Pubertal Suppression and Surgical Management of a Patient with 5-alpha Reductase Deficiency.
Sign Up to like & getrecommendations! Published in 2022 at "Urology"
DOI: 10.1016/j.urology.2022.03.019
Abstract: Five-alpha reductase type 2 deficiency (5αRD2) is a rare cause of atypical genitalia in newborns. There are no definitive guidelines regarding management of children with this disorder. While many children are raised as female given… read more here.
Keywords: patient; management; deficiency; alpha reductase ... See more keywords
Alpha Blocker and 5-Alpha Reductase Inhibitor Prescribing Habits among Urologists and Primary Care Physicians
Sign Up to like & getrecommendations! Published in 2019 at "Urology Practice"
DOI: 10.1097/upj.0000000000000001
Abstract: AbstractIntroduction:While primary care physicians often prescribe medical therapy for voiding symptoms attributed to benign prostate enlargement, it is not clear to what extent they use novel or v... read more here.
Keywords: alpha blocker; care physicians; primary care; alpha reductase ... See more keywords
Pre-treatment PSA- progression as a negative prognostic factor in patients using 5-alpha-reductase inhibitors prior to radiotherapy for prostate cancer.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.6_suppl.96
Abstract: 96Background: To investigate the impact of 5-alpha-reductase inhibitors (5-ARIs) usage on radiotherapy outcomes for localized prostate cancer. Methods: From our institutional database of over 2500 patients, we identified 203 patients on a 5-ARI. They were… read more here.
Keywords: psa progression; alpha reductase; prostate cancer; cancer ... See more keywords
Phytochemicals With Anti 5-alpha-reductase Activity: A Prospective For Prostate Cancer Treatment
Sign Up to like & getrecommendations! Published in 2021 at "F1000Research"
DOI: 10.12688/f1000research.51066.3
Abstract: Prostate cancer (CaP) is one of the leading causes of death in men worldwide. Much attention has been given on its prevention and treatment strategies, including targeting the regulation of 5-alpha-Reductase (5αR) enzyme activity, aimed… read more here.
Keywords: alpha reductase; treatment; cap; prostate cancer ... See more keywords
The continuing debate of 5-alpha reductase inhibitors and prostate cancer risk
Sign Up to like & getrecommendations! Published in 2018 at "Translational cancer research"
DOI: 10.21037/23887
Abstract: Finasteride and dutasteride are 5-alpha reductase inhibitors (5-ARIs) which have been shown to improve symptoms of benign prostatic hyperplasia (BPH) and reduce the risk of urinary retention and BPH-related surgeries (1,2). These medications inhibit the… read more here.
Keywords: risk; alpha reductase; prostate cancer; cancer ... See more keywords
5-alpha reductase inhibitors use in prostatic disease and beyond
Sign Up to like & getrecommendations! Published in 2023 at "Translational Andrology and Urology"
DOI: 10.21037/tau-22-690
Abstract: 5-alpha reductase inhibitors (5-ARIs) are commonly used and widely available, with benefits observed from their effect on androgen signalling. Their effect relies on the inhibition of the 5-alpha reductase enzyme which aids in the conversion… read more here.
Keywords: prostate cancer; alpha reductase; pharmacology; reductase inhibitors ... See more keywords