Articles with "alpha spending" as a keyword



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A Bayesian sequential design using alpha spending function to control type I error

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Published in 2017 at "Statistical Methods in Medical Research"

DOI: 10.1177/0962280215595058

Abstract: We propose in this article a Bayesian sequential design using alpha spending functions to control the overall type I error in phase III clinical trials. We provide algorithms to calculate critical values, power, and sample… read more here.

Keywords: bayesian sequential; sequential design; alpha spending; power ... See more keywords