G Protein Signaling in Plants: Characterization of Alpha and Gamma Subunits
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2016.11.1052
Abstract: In plants heterotrimeric complexes of G proteins (consisting of alpha, beta, and gamma subunits) regulate several signaling pathways including seed germination, seedling development, organ shape and size determination. The alpha subunit has GTP binding and… read more here.
Keywords: gamma subunits; subunits protein; protein signaling; alpha subunit ... See more keywords
G-Alpha Subunit Abundance and Activity Differentially Regulate β-Catenin Signaling
Sign Up to like & getrecommendations! Published in 2018 at "Molecular and Cellular Biology"
DOI: 10.1128/mcb.00422-18
Abstract: Heterotrimeric G proteins are signal transduction proteins involved in regulating numerous signaling events. In particular, previous studies have demonstrated a role for G-proteins in regulating β-catenin signaling. ABSTRACT Heterotrimeric G proteins are signal transduction proteins… read more here.
Keywords: catenin signaling; catenin; subunit abundance; alpha subunit ... See more keywords
Sodium channel protein alpha subunit genomics: building an integrated knowledgebase to translate between family members
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5735085
Abstract: The sodium channel alpha proteins consist of ten homologous human proteins (SCN1A, SCN2A, SCN3A, SCN4A, SCN5A, SCN7A, SCN8A, SCN9A, SCN10A, SCN11A), many involved in various human physiological pathways and clinical disorders/syndromes. Many human variants connected… read more here.
Keywords: amino acids; family; family members; alpha subunit ... See more keywords
Complex interactions between p.His558Arg and linked variants in the sodium voltage-gated channel alpha subunit 5 (NaV1.5)
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DOI: 10.7717/peerj.13913
Abstract: Common genetic polymorphisms may modify the phenotypic outcome when co-occurring with a disease-causing variant, and therefore understanding their modulating role in health and disease is of great importance. The polymorphic p.His558Arg variant of the sodium… read more here.
Keywords: voltage gated; sodium voltage; gated channel; alpha subunit ... See more keywords