A comprehensive ethnic-based analysis of alpha thalassaemia allelle frequency in northern Thailand
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-04957-2
Abstract: Alpha (α)-thalassaemia is one of the most prevalent hereditary blood disorders, commonly affecting Southeast Asian people, with the highest incidence (30–40%) being seen in northern Thailand. However, this high incidence was estimated without consideration of… read more here.
Keywords: alpha thalassaemia; northern thailand; thalassaemia; allele frequency ... See more keywords
Mitochondrial ferritin expression in erythroid cells from patients with alpha-thalassaemia
Sign Up to like & getrecommendations! Published in 2018 at "Hematology"
DOI: 10.1080/10245332.2018.1496812
Abstract: ABSTRACT Background: Patients with thalassaemia who received regular transfusions had increased iron accumulation, leading to iron overload, which was associated with oxidative stress. Mitochondrial ferritin, encoded by the FTMT gene is an iron-storage protein in… read more here.
Keywords: mitochondrial ferritin; alpha thalassaemia; ferritin; patients alpha ... See more keywords
Inherited haemochromatosis with C282Y mutation in a patient with alpha-thalassaemia: a treatment dilemma
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DOI: 10.1136/bcr-2017-222700
Abstract: A Caucasian 24-year-old female patient suffers from two hereditary disorders: alpha-thalassaemia, which is prevalent in Asia and rare in Europe, and haemochromatosis, which is prevalent among northern Europe and rare in Asia. The clinical presentation… read more here.
Keywords: alpha thalassaemia; treatment; iron; haemochromatosis ... See more keywords
Gene Mutation Spectrum among Alpha-Thalassaemia Patients in Northeast Peninsular Malaysia
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DOI: 10.3390/diagnostics13050894
Abstract: (1) Background: Alpha (α)-thalassaemia is a genetic disorder that affects 5% of the world population. Deletional or nondeletional mutations of one or both HBA1 and HBA2 on chromosome 16 will result in reduced production of… read more here.
Keywords: alpha thalassaemia; gene mutation; mutation spectrum; sea ... See more keywords