A broader context for understanding amino acid alphabet optimality.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of theoretical biology"
DOI: 10.1016/j.jtbi.2021.110661
Abstract: A series of prior publications has reported unusual properties of the set of genetically encoded amino acids shared by all known life. This work uses quantitative measures (descriptors) of size, charge and hydrophobicity to compare… read more here.
Keywords: encoded amino; alphabet; amino; amino acid ... See more keywords
Tautomeric Equilibria of Nucleobases in the Hachimoji Expanded Genetic Alphabet.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of chemical theory and computation"
DOI: 10.1021/acs.jctc.9b01079
Abstract: Evolution has yielded biopolymers that are constructed from exactly four building blocks and are able to support Darwinian evolution. Synthetic biology aims to extend this alphabet, and we recently showed that 8-letter (hachimoji) DNA can… read more here.
Keywords: hachimoji; alphabet; expanded genetic; genetic alphabet ... See more keywords
Early Selection of the Amino Acid Alphabet Was Adaptively Shaped by Biophysical Constraints of Foldability
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c12987
Abstract: Whereas modern proteins rely on a quasi-universal repertoire of 20 canonical amino acids (AAs), numerous lines of evidence suggest that ancient proteins relied on a limited alphabet of 10 ‘early’ AAs, and that the 10… read more here.
Keywords: amino acids; acid alphabet; alphabet; amino acid ... See more keywords
Minimax Compression and Large Alphabet Approximation Through Poissonization and Tilting
Sign Up to like & getrecommendations! Published in 2017 at "IEEE Transactions on Information Theory"
DOI: 10.1109/tit.2017.2661990
Abstract: This paper introduces a convenient strategy for coding and predicting sequences of independent, identically distributed random variables generated from a large alphabet of size $m$ . In particular, the size of the sample is allowed… read more here.
Keywords: large alphabet; alphabet approximation; alphabet; minimax compression ... See more keywords
A Construction of Maximum Distance Profile Convolutional Codes With Small Alphabet Sizes
Sign Up to like & getrecommendations! Published in 2023 at "IEEE Transactions on Information Theory"
DOI: 10.1109/tit.2023.3236425
Abstract: Convolutional codes are essential in a wide range of practical applications due to their efficient non-algebraic decoding algorithms. In this paper, we first propose a new family of matrices over finite fields by combining Vandermonde… read more here.
Keywords: distance profile; maximum distance; alphabet; convolutional codes ... See more keywords
QWERTY in China: Chinese Computing and the Radical Alphabet
Sign Up to like & getrecommendations! Published in 2018 at "Technology and Culture"
DOI: 10.1353/tech.2018.0149
Abstract: ABSTRACT:Since the late 1980s, computers throughout the Sinophone world have featured QWERTY keyboards, employing input techniques that rely upon the Latin alphabet. In this article, I argue that historians of modern China and modern information… read more here.
Keywords: china chinese; alphabet; china; qwerty china ... See more keywords