Alphavirus nsP2: A Multifunctional Regulator of Viral Replication and Promising Target for Anti‐Alphavirus Therapies
Sign Up to like & getrecommendations! Published in 2025 at "Reviews in Medical Virology"
DOI: 10.1002/rmv.70030
Abstract: Alphaviruses are re‐emerging vector‐born pathogens that cause arthralgia or encephalitic diseases on a global scale. While a vaccine against chikungunya virus was recently approved, no vaccines currently exist for other alphaviruses, nor are there antiviral… read more here.
Keywords: regulator viral; replication; alphavirus nsp2; nsp2 multifunctional ... See more keywords
Development and evaluation of indirect double-antibody sandwich ELISA for rapid detection of Salmonid Alphavirus using Baculoviridae expressed E1 Protein
Sign Up to like & getrecommendations! Published in 2021 at "Aquaculture"
DOI: 10.1016/j.aquaculture.2021.737081
Abstract: Abstract Salmon alphavirus (SAV) is a widespread virus that infects Atlantic salmon (Salmo salar) and rainbow trout (Oncorhynchus mykiss) in Europe. It has a fatality rate of ≤48% and can cause pancreatic and sleeping disease.… read more here.
Keywords: double antibody; indirect double; alphavirus; antibody sandwich ... See more keywords
Deinococcus Mn2+-peptide complex: A novel approach to alphavirus vaccine development.
Sign Up to like & getrecommendations! Published in 2017 at "Vaccine"
DOI: 10.1016/j.vaccine.2017.05.016
Abstract: Over the last ten years, Chikungunya virus (CHIKV), an Old World alphavirus has caused numerous outbreaks in Asian and European countries and the Americas, making it an emerging pathogen of great global health importance. Venezuelan… read more here.
Keywords: novel approach; approach; vaccine; alphavirus ... See more keywords
Discovery of Mwinilunga alphavirus: A novel alphavirus in Culex mosquitoes in Zambia.
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DOI: 10.1016/j.virusres.2018.04.005
Abstract: Mosquito-borne alphaviruses are disseminated globally and cause febrile illness in humans and animals. Since the prevalence and diversity of alphaviruses has not been previously investigated in Zambia, reverse transcription PCR was employed as a broad-spectrum… read more here.
Keywords: mosquito; novel alphavirus; culex; mwinilunga alphavirus ... See more keywords
Characterization of an alphavirus isolated from a stranded harbor porpoise (Phocoena phocoena) from Alaska.
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DOI: 10.1016/j.virusres.2020.198187
Abstract: The family Togaviridae comprises several significant human and veterinary mosquito-borne pathogens. Two togaviruses (genus Alphavirus) have been previously identified in association with marine mammals, the southern elephant seal virus (SESV) and Eastern equine encephalitis (EEEV)… read more here.
Keywords: porpoise phocoena; phocoena; alphavirus; harbor porpoise ... See more keywords
nsP4 Is a Major Determinant of Alphavirus Replicase Activity and Template Selectivity
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DOI: 10.1128/jvi.00355-21
Abstract: A key element of every virus with an RNA genome is the RNA replicase. Understanding the principles of RNA replicase formation and functioning is therefore crucial for understanding and responding to the emergence of new… read more here.
Keywords: rna replicase; formation; p123; virus ... See more keywords
Chikungunya Virus Strains from Each Genetic Clade Bind Sulfated Glycosaminoglycans as Attachment Factors
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Virology"
DOI: 10.1128/jvi.01500-20
Abstract: Alphavirus infections are a global health threat, contributing to outbreaks of disease in many parts of the world. Recent epidemics caused by CHIKV, an arthritogenic alphavirus, resulted in more than 8.5 million cases as the… read more here.
Keywords: chikv binding; attachment factors; virus; strain ... See more keywords
The First Isolation of Insect-Specific Alphavirus (Agua Salud alphavirus) in Culex (Melanoconion) Mosquitoes in the Brazilian Amazon
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DOI: 10.3390/v16091355
Abstract: Advances in diagnostic techniques coupled with ongoing environmental changes have resulted in intensified surveillance and monitoring of arbovirus circulation in the Amazon. This increased effort has resulted in increased detection of insect-specific viruses among hematophagous… read more here.
Keywords: amazon; salud alphavirus; agua salud; alphavirus ... See more keywords