Cryo-EM structures of alphavirus conformational intermediates in low pH–triggered prefusion states
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2114119119
Abstract: Significance Eastern equine encephalitis virus (EEEV) is a neuroinvasive alphavirus that causes severe neurological diseases. Entry of alphaviruses requires host–virus membrane fusion in endosomes to release the RNA genome into the cytosol for virus replication.… read more here.
Keywords: fusion; membrane fusion; cryo structures; alphavirus conformational ... See more keywords