ALPK1 regulates streptozotocin‐induced nephropathy through CCL2 and CCL5 expressions
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DOI: 10.1111/jcmm.14643
Abstract: ALPK1 is associated with chronic kidney disease, gout and type 2 diabetes mellitus. Raised renal ALPK1 level in patients with diabetes was reported. Accelerated fibrotic nephropathies were observed in hyperglycaemic mice with up‐regulated ALPK1. The… read more here.
Keywords: alpk1; ccl5; ccl5 expressions; ccl2 ccl5 ... See more keywords
ALPK1 Aggravates TMJOA Cartilage Degradation via NF-κB and ERK1/2 Signaling
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Dental Research"
DOI: 10.1177/00220345221100179
Abstract: Temporomandibular joint osteoarthritis (TMJOA) is a common degenerative joint disease without effective intervention strategies. Previous research implied that alpha-kinase 1 (ALPK1) is involved in the inflammatory responses of gout, a chronic arthritis. Herein, we found… read more here.
Keywords: erk1 signaling; pathology; alpk1; condylar cartilage ... See more keywords
Systematic Review of the Role of Alpha-Protein Kinase 1 in Cancer and Cancer-Related Inflammatory Diseases
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DOI: 10.3390/cancers14184390
Abstract: Simple Summary Aside from the basic phosphorylation function of alpha-kinase 1 (ALPK1), little is known about its major functions. Researchers have used various forms of biotechnology and human, animal, and cellular models to better understand… read more here.
Keywords: cancer related; kinase; cancer cancer; alpk1 ... See more keywords