Abstract LB011: Development of novel protein drug conjugates (PDCs) for the selective targeting of ALPP/ALPPL2 expressing tumors
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DOI: 10.1158/1538-7445.am2023-lb011
Abstract: The placental alkaline phosphatases, ALPP and ALPPL2, are glycosylphosphatidylinositol (GPI)-anchored cell-surface proteins that are expressed in the placenta during fetal development but have very little expression on normal adult tissue. These proteins are over-expressed in… read more here.
Keywords: development; drug conjugates; alpp alppl2; drug ... See more keywords