Glymphatic system dysfunction in patients with juvenile myoclonic epilepsy
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Neurology"
DOI: 10.1007/s00415-021-10799-w
Abstract: The glymphatic system is a glial cell-dependent waste clearance pathway in the brain that is essential for the maintenance of brain homeostasis. In this study, we evaluated glymphatic system function in patients with juvenile myoclonic… read more here.
Keywords: system function; system; alps index; patients jme ... See more keywords
The aging of glymphatic system in human brain and its correlation with brain charts and neuropsychological functioning.
Sign Up to like & getrecommendations! Published in 2023 at "Cerebral cortex"
DOI: 10.1093/cercor/bhad086
Abstract: This study aimed to investigate the aging of the glymphatic system in healthy adults, and to determine whether this change is correlated with the brain charts and neuropsychological functioning. Two independent brain 3.0 T MRI datasets… read more here.
Keywords: brain; neuropsychological functioning; brain charts; alps index ... See more keywords
Gray Matter Reserve Determines Glymphatic System Function in Young-Onset Alzheimer's Disease: Evidenced by DTI-ALPS and Compared with Age-matched Controls.
Sign Up to like & getrecommendations! Published in 2023 at "Psychiatry and clinical neurosciences"
DOI: 10.1111/pcn.13557
Abstract: BACKGROUND The diffusion tensor imaging analysis along the perivascular space (ALPS)-index can be used to model the glymphatic system in vivo. AIM This study explores putative mechanisms between prediction of ALPS-index and cognitive outcomes in… read more here.
Keywords: index; onset alzheimer; alps index; young onset ... See more keywords
Altered Brain Glymphatic Flow at Diffusion-Tensor MRI in Rapid Eye Movement Sleep Behavior Disorder.
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DOI: 10.1148/radiol.221848
Abstract: Background Brain glymphatic dysfunction may contribute to the development of α-synucleinopathies. Yet, noninvasive imaging and quantification remain lacking. Purpose To examine glymphatic function of the brain in isolated rapid eye movement sleep behavior disorder (RBD)… read more here.
Keywords: brain glymphatic; brain; mri; alps index ... See more keywords
Associations among Cognitive Functions, Plasma DNA, and Diffusion Tensor Image along the Perivascular Space (DTI-ALPS) in Patients with Parkinson's Disease
Sign Up to like & getrecommendations! Published in 2021 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2021/4034509
Abstract: Background Parkinson's disease (PD) is a common neurodegenerative disease associated with accumulation of misfolding proteins and increased neuroinflammation, which may further impair the glymphatic system. The purpose of this study was to utilize diffusion tensor… read more here.
Keywords: alps index; perivascular space; plasma dna; along perivascular ... See more keywords
Evaluation of the Glymphatic System Using the DTI-ALPS Index in Patients with Spontaneous Intracerebral Haemorrhage
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/2694316
Abstract: Objective To investigate the function of the human glymphatic system (GS) in patients with spontaneous intracerebral haemorrhage (sICH) using diffusion tensor imaging analysis along with the perivascular space (DTI-ALPS). Methods Twenty patients with sICH and… read more here.
Keywords: dti alps; glymphatic system; alps index; side ... See more keywords
The Influence of Demographics and Vascular Risk Factors on Glymphatic Function Measured by Diffusion Along Perivascular Space
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2021.693787
Abstract: Assessing glymphatic function using in-vivo imaging method is of great value for understanding its contribution to major brain diseases. In the present study, we aim to validate the association between a variety of risk factors… read more here.
Keywords: index; glymphatic function; diffusion; alps index ... See more keywords
Water Diffusivity Changes Along the Perivascular Space After Lumboperitoneal Shunt Surgery in Idiopathic Normal Pressure Hydrocephalus
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2022.843883
Abstract: Background The aim of this study was to evaluate the water diffusivity changes along the perivascular space after lumboperitoneal shunt (LPS) surgery in idiopathic normal pressure hydrocephalus. Methods Nine patients diagnosed with idiopathic normal pressure… read more here.
Keywords: surgery; alps index; operative inph; index ... See more keywords
Glymphatic system dysfunction in patients with early chronic kidney disease
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2022.976089
Abstract: Introduction It is a recent finding that glymphatic system dysfunction contributes to various neurological problems. The purpose of this research was to assess the function of the glymphatic system in neurologically asymptomatic early chronic kidney… read more here.
Keywords: dti; dti alps; alps index; patients early ... See more keywords
Glymphatic system impairment in nonathlete older male adults who played contact sports in their youth associated with cognitive decline: A diffusion tensor image analysis along the perivascular space study
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2023.1100736
Abstract: Background and purpose Exposure to contact sports in youth causes brain health problems later in life. For instance, the repetitive head impacts in contact sports might contribute to glymphatic clearance impairment and cognitive decline. This… read more here.
Keywords: contact; alps index; age years; cognitive decline ... See more keywords
Increased glymphatic system activity in patients with mild traumatic brain injury
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2023.1148878
Abstract: Purpose This study aims to investigate the glymphatic system activity changes in patients with mild traumatic brain injury (mTBI), particularly in MRI-negative patients, using analysis along the perivascular space (ALPS) technology. Methods A total of… read more here.
Keywords: index; brain; activity; alps index ... See more keywords