Association of Serum Retinol-Binding Protein 4 Concentration With Risk for and Prognosis of Amyotrophic Lateral Sclerosis
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DOI: 10.1001/jamaneurol.2017.5129
Abstract: Importance Knowledge about the metabolic states of patients with amyotrophic lateral sclerosis (ALS) may provide a therapeutic approach. Objective To investigate the association between the onset and prognosis of ALS and serum retinol-binding protein 4… read more here.
Keywords: als cases; risk; prognosis; association ... See more keywords
TDP-43 protein variants as biomarkers in amyotrophic lateral sclerosis
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DOI: 10.1186/s12868-017-0334-7
Abstract: BackgroundTDP-43 aggregates accumulate in individuals affected by amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases, representing potential diagnostic and therapeutic targets. Using an atomic force microscopy based biopanning protocol developed in our lab, we previously… read more here.
Keywords: als cases; tdp; amyotrophic lateral; tdp variants ... See more keywords
Increased Risk of Venous Thromboembolism in Patients With Amyotrophic Lateral Sclerosis
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DOI: 10.1212/cpj.0000000000200110
Abstract: Background and Objectives Reduced mobility in patients with amyotrophic lateral sclerosis (ALS) is hypothesized to increase the risk of venous thromboembolism (VTE). A few small, single-center studies have investigated the risk of VTE in patients… read more here.
Keywords: patients amyotrophic; patients als; vte; risk ... See more keywords
The underacknowledged PPA-ALS
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DOI: 10.1212/wnl.0000000000007146
Abstract: Objective To assess the incidence, heritability, and neuropathology of primary progressive aphasia (PPA) with amyotrophic lateral sclerosis (ALS) in a large Australian cohort. Methods A total of 130 patients with a primary nonfluent variant of… read more here.
Keywords: strong family; underacknowledged ppa; ppa; family history ... See more keywords