Articles with "als clinical" as a keyword



Reply to: Frequent self‐assessments in ALS clinical trials: Worthwhile or an unnecessary burden?

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Published in 2020 at "Annals of Clinical and Translational Neurology"

DOI: 10.1002/acn3.51177

Abstract: Reply to: Frequent self-assessments in ALS clinical trials: Worthwhile or an unnecessary burden? Seward B. Rutkove , Pushpa Narayanaswami, Visar Berisha, Julie Liss, Shira Hahn, Kerisa Shelton, Kristin Qi, Sarbesh Pandeya & Jeremy M. Shefner… read more here.

Keywords: frequent self; reply frequent; assessments als; clinical trials ... See more keywords

Yentl syndrome, a real phenomenon in amyotrophic lateral sclerosis (ALS)?

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Published in 2025 at "Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration"

DOI: 10.1080/21678421.2024.2432030

Abstract: Abstract Introduction: ALS, a neurodegenerative disorder, exhibits variable incidence and prevalence across various databases consulted. Among these, PRO-ACT stands out as the most extensive publicly accessible repository of aggregated ALS clinical trial information. The estimated… read more here.

Keywords: als clinical; yentl syndrome; phenomenon; amyotrophic lateral ... See more keywords

ALS Clinical Trials Review: 20 Years of Failure. Are We Any Closer to Registering a New Treatment?

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Published in 2017 at "Frontiers in Aging Neuroscience"

DOI: 10.3389/fnagi.2017.00068

Abstract: Amyotrophic lateral sclerosis (ALS) is a devastating condition with an estimated mortality of 30,000 patients a year worldwide. The median reported survival time since onset ranges from 24 to 48 months. Riluzole is the only… read more here.

Keywords: treatment; clinical trials; masitinib; edaravone ... See more keywords
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Cortical Excitability across the ALS Clinical Motor Phenotypes

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Published in 2021 at "Brain Sciences"

DOI: 10.3390/brainsci11060715

Abstract: Amyotrophic lateral sclerosis (ALS) is characterized by its marked clinical heterogeneity. Although the coexistence of upper and lower motor neuron signs is a common clinical feature for most patients, there is a wide range of… read more here.

Keywords: across als; motor phenotypes; cortical excitability; motor ... See more keywords