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   Articles with "als patient" as a keyword



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Discussing edaravone with the ALS patient: an ethical framework from a U.S. perspective

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recommendations! Published in 2018 at "Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration"

DOI: 10.1080/21678421.2018.1425455

Abstract: Abstract The recent approval of edaravone by the United States Food and Drug Administration has generated a mix of hope tempered by reality. The costs of the drug, both monetarily and with regard to intensity… read more here.

Keywords: ethical framework; patient ethical; discussing edaravone; als patient ... See more keywords
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Concurrence of NMOSD and ALS in a patient with hexanucleotide repeat expansions of C9orf72

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recommendations! Published in 2019 at "Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration"

DOI: 10.1080/21678421.2019.1604761

Abstract: Abstract We describe a patient, previously known for NMOSD, who presented a rapidly progressive worsening of muscle strength, respiratory, and bulbar functions. ALS associated with cognitive impairment was diagnosed, while genetic analysis revealed a hexanucleotide… read more here.

Keywords: concurrence nmosd; repeat expansions; patient hexanucleotide; nmosd als ... See more keywords
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NEK1 and GRN mutations coexist in a sporadic Chinese Hui descent ALS patient

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recommendations! Published in 2020 at "Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration"

DOI: 10.1080/21678421.2020.1779301

Abstract: Abstract We describe a sporadic amyotrophic lateral sclerosis (ALS) patient who presented rapid progress of muscle weakness and died of respiratory failure one and a half years after onset. Genetic analysis revealed a novel ALS-causing… read more here.

Keywords: mutations coexist; nek1 grn; grn mutations; sporadic chinese ... See more keywords
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Autophagy-Mediated Inflammatory Cytokine Secretion in Sporadic ALS Patient iPSC-Derived Astrocytes

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recommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"

DOI: 10.1155/2022/6483582

Abstract: Background Astrocytes can be involved in motor neuron toxicity in amyotrophic lateral sclerosis (ALS) induced by noncell autonomous effects, and inflammatory cytokines may play the main role in mediating this process. However, the etiology of… read more here.

Keywords: als astrocytes; control; als patient; mtor ... See more keywords