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Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2220984120
Abstract: Significance A rare neurodegenerative disorder endemic to Guam features several types of protein lesions scattered throughout the nervous system and manifests clinical signs of amyotrophic lateral sclerosis, parkinsonism, and dementia. Despite many genetic and environmental…
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Keywords:
distinct double;
pdc distinct;
tau prions;
guam als ... See more keywords
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1
Published in 2020 at "Antioxidants"
DOI: 10.3390/antiox9050423
Abstract: Amyotrophic lateral sclerosis and Parkinsonism-dementia complex (ALS/PDC) is a unique endemic neurodegenerative disease, with high-incidence foci in Kii Peninsula, Japan. To gather new insights into the pathological mechanisms underlying Kii ALS/PDC, we performed transcriptome analyses…
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Keywords:
kii als;
stress responsive;
transcriptome analysis;
als pdc ... See more keywords