In silico investigation of Alsin RLD conformational dynamics and phosphoinositides binding mechanism
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DOI: 10.1371/journal.pone.0270955
Abstract: Alsin is a protein known for its major role in neuronal homeostasis and whose mutation is associated with early-onset neurodegenerative diseases. It has been shown that its relocalization from the cytoplasm to the cell membrane… read more here.
Keywords: alsin rld; silico investigation; alsin; conformational dynamics ... See more keywords
ALS2-Related Motor Neuron Diseases: From Symptoms to Molecules
Sign Up to like & getrecommendations! Published in 2022 at "Biology"
DOI: 10.3390/biology11010077
Abstract: Simple Summary Mutations of the ALS2 gene, which encodes for the protein Alsin, are linked to three recessive motor neuron diseases characterized by early onset. Alsin is an intriguing protein characterized by several structured domains… read more here.
Keywords: als2 related; alsin; neuron diseases; motor neuron ... See more keywords