Alstrom syndrome: insulin resistance in young with congestive heart failure
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Diabetes in Developing Countries"
DOI: 10.1007/s13410-019-00738-x
Abstract: Alstrom Hallgren syndrome is a rare ciliopathy first described in 1959. It is characterised by progressive cone-rod dystrophy leading to blindness, sensorineural hearing loss, childhood obesity and congestive heart failure. Its pathogenesis is related to… read more here.
Keywords: heart; alstrom syndrome; heart failure; insulin resistance ... See more keywords
Characterization of Alstrom Syndrome 1 (ALMS1) Transcript Variants in Hodgkin Lymphoma Cells
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DOI: 10.1371/journal.pone.0170694
Abstract: The Alstrom syndrome gene (ALMS1) is one of the largest disease associated genes identified today in the human genome and is implicated in cell cycle control, ciliogenesis, endosome recycling and intracellular transport mechanisms. ALMS1 mutations… read more here.
Keywords: hodgkin lymphoma; alstrom syndrome; lymphoma cells; transcript variants ... See more keywords
Alstrom syndrome gene is a stem-cell-specific regulator of centriole duplication in the Drosophila testis
Sign Up to like & getrecommendations! Published in 2020 at "eLife"
DOI: 10.7554/elife.59368
Abstract: Asymmetrically dividing stem cells often show asymmetric behavior of the mother versus daughter centrosomes, whereby the self-renewing stem cell selectively inherits the mother or daughter centrosome. Although the asymmetric centrosome behavior is widely conserved, its… read more here.
Keywords: stem cell; centriole duplication; cell specific; alstrom syndrome ... See more keywords