Articles with "alt ast" as a keyword



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Genome‐wide association analysis of serum alanine and aspartate aminotransferase, and the modifying effects of BMI in 388k European individuals

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Published in 2021 at "Genetic Epidemiology"

DOI: 10.1002/gepi.22392

Abstract: Serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) are biomarkers for liver health. Here we report the largest genome‐wide association analysis to date of serum ALT and AST levels in over 388k people of European… read more here.

Keywords: genome wide; alt ast; serum alanine; serum ... See more keywords

Effect of Bariatric Surgery on Serum Enzyme Status in Obese Patients

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Published in 2020 at "Obesity Surgery"

DOI: 10.1007/s11695-020-04554-9

Abstract: Background Scarce data exists about serum enzyme in bariatric patients. We attempted to evaluate serum enzyme status in patients receiving Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) and to identify related predictors. Methods We… read more here.

Keywords: alt ast; hbdh; serum; serum enzyme ... See more keywords

Effects of Selenium on Arsenic-Induced Liver Lesions in Broilers

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Published in 2020 at "Biological Trace Element Research"

DOI: 10.1007/s12011-020-02222-8

Abstract: The aim of the present study was to investigate the abilities of selenium to counteract the toxic damage of arsenic (As). Two hundred 1-day-old healthy male broilers were randomly divided into five groups and fed… read more here.

Keywords: alt ast; group group; inos tnos; group ... See more keywords

Managing Aminotransferase Elevations in Patients with Friedreich Ataxia Treated with Omaveloxolone: A Review and Expert Opinion on Use Considerations

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Published in 2025 at "Neurology and Therapy"

DOI: 10.1007/s40120-025-00752-8

Abstract: Omaveloxolone is approved for the treatment of Friedreich ataxia (FA) in patients aged ≥ 16 years and is under clinical development for pediatric patients. In the MOXIe study, alanine and aspartate aminotransferase (ALT and AST)… read more here.

Keywords: aminotransferase elevations; treatment; use considerations; friedreich ataxia ... See more keywords

Effects of small sided football and date seed (Phoenix dactylifera) powder supplementation on liver enzymes in inactive college subjects: an interventional study

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Published in 2025 at "Journal of the International Society of Sports Nutrition"

DOI: 10.1080/15502783.2025.2532686

Abstract: ABSTRACT Purpose In recent years, the rising prevalence of metabolic disorders and liver dysfunction due to sedentary lifestyles and poor nutrition has become a growing health concern. This study investigates the effects of small sided… read more here.

Keywords: supplementation; football; seed; dsp ... See more keywords

Elevated serum hepatic transaminases in apical periodontitis individuals.

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Published in 2024 at "International endodontic journal"

DOI: 10.1111/iej.14109

Abstract: AIM Apical periodontitis (AP) is the chronic inflammation of the periradicular tissues in response to root canal infection. Whilst AP has been linked with systemic inflammation and noncommunicable diseases, its potential association with nonalcoholic fatty… read more here.

Keywords: ast levels; apical periodontitis; hepatic transaminases; serum hepatic ... See more keywords

Pharmacokinetics of Ceftazidime-Avibactam in Combination with Aztreonam (COMBINE) in a Phase 1, Open-Label Study of Healthy Adults

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Published in 2022 at "Antimicrobial Agents and Chemotherapy"

DOI: 10.1128/aac.00936-22

Abstract: Scant pharmacokinetic (PK) data are available on ceftazidime-avibactam (CZA) and aztreonam (ATM) in combination, and it is unknown if CZA-ATM exacerbates alanine aminotransferase (ALT)/aspartate aminotransferase (AST) elevations relative to ATM alone. This phase 1 study… read more here.

Keywords: alt ast; cza atm; cza; ast elevations ... See more keywords
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Liver injury is independently associated with adverse clinical outcomes in patients with COVID-19

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Published in 2020 at "Gut"

DOI: 10.1136/gutjnl-2020-321726

Abstract: Objective Data on serial liver biochemistries of patients infected by different human coronaviruses (HCoVs) are lacking. The impact of liver injury on adverse clinical outcomes in coronavirus disease 2019 (COVID-19) patients remains unclear. Design This… read more here.

Keywords: alt ast; clinical outcomes; ast elevation; independently associated ... See more keywords

Association between ALT/AST and Muscle Mass in Patients with Type 2 Diabetes Mellitus

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Published in 2022 at "Mediators of Inflammation"

DOI: 10.1155/2022/9480228

Abstract: Objective The alanine aminotransferase/aspartate aminotransferase (ALT/AST) ratio is thought to be related to metabolic disorders and insulin resistance. Type 2 diabetes mellitus (T2DM) is a high-risk population for low muscle mass. This study was performed… read more here.

Keywords: association alt; alt ast; muscle; muscle mass ... See more keywords

ALT/AST as an Independent Risk Factor of Gestational Diabetes Mellitus Compared with TG/HDL-C

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Published in 2022 at "International Journal of General Medicine"

DOI: 10.2147/ijgm.s332946

Abstract: Objective This study aimed to find the association between alanine transaminase-to-aspartate aminotransferase ratio (ALT/AST) and the incidence of gestational diabetes mellitus (GDM). Methods A total of 1128 pregnant women were included in this prospective, double-center,… read more here.

Keywords: independent risk; alt ast; alt; gestational diabetes ... See more keywords

Associations of ALT, AST and ALT/AST ratio with metabolically unhealthy obesity in the elderly

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Published in 2025 at "Frontiers in Nutrition"

DOI: 10.3389/fnut.2025.1513029

Abstract: Aims This study aimed to clarify the effects of alanine aminotransferase (ALT), aspartate aminotransferase (AST) and ALT/AST ratio on metabolically unhealthy obese (MUHO) and to estimate the predictors of MUHO in the elderly. Methods 19,812… read more here.

Keywords: ast alt; ast ratio; alt; ratio metabolically ... See more keywords