Genome‐wide association analysis of serum alanine and aspartate aminotransferase, and the modifying effects of BMI in 388k European individuals
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DOI: 10.1002/gepi.22392
Abstract: Serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) are biomarkers for liver health. Here we report the largest genome‐wide association analysis to date of serum ALT and AST levels in over 388k people of European… read more here.
Keywords: genome wide; alt ast; serum alanine; serum ... See more keywords
Effect of Bariatric Surgery on Serum Enzyme Status in Obese Patients
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DOI: 10.1007/s11695-020-04554-9
Abstract: Background Scarce data exists about serum enzyme in bariatric patients. We attempted to evaluate serum enzyme status in patients receiving Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) and to identify related predictors. Methods We… read more here.
Keywords: alt ast; hbdh; serum; serum enzyme ... See more keywords
Effects of Selenium on Arsenic-Induced Liver Lesions in Broilers
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DOI: 10.1007/s12011-020-02222-8
Abstract: The aim of the present study was to investigate the abilities of selenium to counteract the toxic damage of arsenic (As). Two hundred 1-day-old healthy male broilers were randomly divided into five groups and fed… read more here.
Keywords: alt ast; group group; inos tnos; group ... See more keywords
Pharmacokinetics of Ceftazidime-Avibactam in Combination with Aztreonam (COMBINE) in a Phase 1, Open-Label Study of Healthy Adults
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DOI: 10.1128/aac.00936-22
Abstract: Scant pharmacokinetic (PK) data are available on ceftazidime-avibactam (CZA) and aztreonam (ATM) in combination, and it is unknown if CZA-ATM exacerbates alanine aminotransferase (ALT)/aspartate aminotransferase (AST) elevations relative to ATM alone. This phase 1 study… read more here.
Keywords: alt ast; cza atm; cza; ast elevations ... See more keywords
Liver injury is independently associated with adverse clinical outcomes in patients with COVID-19
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DOI: 10.1136/gutjnl-2020-321726
Abstract: Objective Data on serial liver biochemistries of patients infected by different human coronaviruses (HCoVs) are lacking. The impact of liver injury on adverse clinical outcomes in coronavirus disease 2019 (COVID-19) patients remains unclear. Design This… read more here.
Keywords: alt ast; clinical outcomes; ast elevation; independently associated ... See more keywords
Association between ALT/AST and Muscle Mass in Patients with Type 2 Diabetes Mellitus
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DOI: 10.1155/2022/9480228
Abstract: Objective The alanine aminotransferase/aspartate aminotransferase (ALT/AST) ratio is thought to be related to metabolic disorders and insulin resistance. Type 2 diabetes mellitus (T2DM) is a high-risk population for low muscle mass. This study was performed… read more here.
Keywords: association alt; alt ast; muscle; muscle mass ... See more keywords
ALT/AST as an Independent Risk Factor of Gestational Diabetes Mellitus Compared with TG/HDL-C
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DOI: 10.2147/ijgm.s332946
Abstract: Objective This study aimed to find the association between alanine transaminase-to-aspartate aminotransferase ratio (ALT/AST) and the incidence of gestational diabetes mellitus (GDM). Methods A total of 1128 pregnant women were included in this prospective, double-center,… read more here.
Keywords: independent risk; alt ast; alt; gestational diabetes ... See more keywords
Association between Serum Liver Enzymes and Metabolic Syndrome in Korean Adults
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DOI: 10.3390/ijerph15081658
Abstract: The purpose of this study was to evaluate the association between alanine aminotransferase (ALT) and aspartate aminotransferase (AST), and metabolic syndrome (MS) in the Korean population. A total of 11,587 adults ≥30 years of age… read more here.
Keywords: syndrome korean; alt ast; levels alt; association serum ... See more keywords
Clinical and Laboratory Associations with Persistent Hyperferritinemia in 373 Black Hemochromatosis and Iron Overload Screening Study Participants.
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DOI: 10.5604/01.3001.0010.2815
Abstract: BACKGROUND 373 black participants had elevated screening and post-screening serum ferritin (SF) (> 300 |ig/L men; > 200 |ig/L women). MATERIAL AND METHODS We retrospectively studied SF and post-screening age; sex; body mass index; transferrin… read more here.
Keywords: alt ast; 373 black; transfusion; iron overload ... See more keywords