Abstract 2701: Proteogenomic analysis of endoscopy biopsy identifies alterations in apoptotic pathways in trastuzumab-resistant gastric cancers
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DOI: 10.1158/1538-7445.am2018-2701
Abstract: Although the combination of trastuzumab with cisplatin and fluoropyrimidine is standard therapy for metastatic HER2-positive gastric cancers, predictive biomarkers for this therapy need to be further refined. Given the multifactorial nature of clinical trastuzumab resistance,… read more here.
Keywords: biopsy; gastric cancers; resistant tumors; alterations apoptotic ... See more keywords