Articles with "alterations mechanisms" as a keyword



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Epigenetic Alterations and Mechanisms That Drive Resistance to Targeted Cancer Therapies

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Published in 2021 at "Cancer Research"

DOI: 10.1158/0008-5472.can-21-1606

Abstract: Cancer is a complex disease and cancer cells typically harbor multiple genetic and epigenetic alterations. Large-scale sequencing of patient-derived cancer samples has identified several druggable driver oncogenes. Many of these oncogenes can be pharmacologically targeted… read more here.

Keywords: cancer types; resistance targeted; cancer; resistance ... See more keywords