Bortezomib-Induced Epigenetic Alterations in Nerve Cells: Focus on the Mechanisms Contributing to the Peripheral Neuropathy Development
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DOI: 10.3390/ijms23052431
Abstract: Bortezomib-induced peripheral neuropathy (BiPN) occurs in approximately 40% of patients with multiple myeloma. The induction of severe neuropathy entails the dose reduction or complete elimination of bortezomib (BTZ). Interestingly, discontinuation of BTZ mostly results in… read more here.
Keywords: epigenetic alterations; alterations nerve; bortezomib induced; peripheral neuropathy ... See more keywords