Altered gene expression in early postnatal monoamine oxidase A knockout mice
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DOI: 10.1016/j.brainres.2017.05.017
Abstract: We reported previously that monoamine oxidase (MAO) A knockout (KO) mice show increased serotonin (5-hydroxytryptamine, 5-HT) levels and autistic-like behaviors characterized by repetitive behaviors, and anti-social behaviors. We showed that administration of the serotonin synthesis… read more here.
Keywords: monoamine oxidase; knockout mice; altered gene; mice ... See more keywords
Hepatic pathology and altered gene transcription in a murine model of acid ceramidase deficiency
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DOI: 10.1038/s41374-019-0271-4
Abstract: Farber disease (FD) is a rare lysosomal storage disorder (LSD) characterized by systemic ceramide accumulation caused by a deficiency in acid ceramidase (ACDase). In its classic form, FD manifests with painful lipogranulomatous nodules in extremities… read more here.
Keywords: gene transcription; pathology; altered gene; gene ... See more keywords
Altered Gene Response to Aflatoxin B1 in the Spleens of Susceptible and Resistant Turkeys
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DOI: 10.3390/toxins11050242
Abstract: Susceptibility and/or resistance to aflatoxin B1 (AFB1) is a threshold trait governed principally by glutathione S transferase (GST)-mediated detoxification. In poultry, domesticated turkeys are highly sensitive to AFB1, most likely due to dysfunction in hepatic… read more here.
Keywords: gene response; response; altered gene; expression ... See more keywords