Altered glucuronidation deregulates androgen dependent response profiles and signifies castration resistance in prostate cancer
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DOI: 10.18632/oncotarget.28059
Abstract: Glucuronidation controls androgen levels in the prostate and the dysregulation of enzymes in this pathway is associated with castration resistant prostate cancer. UDP-glucose dehydrogenase (UGDH) produces UDP-glucuronate, the essential precursor for glucuronidation, and its expression… read more here.
Keywords: cancer; altered glucuronidation; androgen dependent; prostate cancer ... See more keywords