Altered Peptide Self-Assembly and Co-Assembly with DNA by Modification of Aromatic Residues.
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DOI: 10.1002/cmdc.202100440
Abstract: Aromatic residues are widely used as building blocks for driving self-assemblies in natural and designer biomaterials. The non-covalent interactions involving aromatic rings determine proteins' structure and biofunction. Here, we studied the effects of changes in the proximity of… read more here.
Keywords: self assembly; aromatic residues; peptide self; self ... See more keywords
Biodistribution and pharmacokinetic profiles of an altered peptide ligand derived from heat-shock proteins 60 in Lewis rats
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DOI: 10.1007/s12192-019-01054-3
Abstract: Human heat-shock protein 60 (HSP60) is an autoantigen involved in the pathogenesis of rheumatoid arthritis (RA). Epitopes derived from HSP60 can trigger activation of regulatory T cells (Treg). CIGB-814 is an altered peptide ligand (APL)… read more here.
Keywords: lewis rats; peptide ligand; heat shock; altered peptide ... See more keywords