Altered redox homeostasis and signaling in Cerebral Cavernous Malformation disease: towards a complex but unifying pathogenic mechanism and therapeutic implications
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DOI: 10.1016/j.freeradbiomed.2018.05.055
Abstract: Cerebral Cavernous Malformation (CCM) is a major cerebrovascular disease of genetic origin affecting 0.3-0.5% of the population and still awaiting therapies other than neurosurgery. It is characterized by abnormally enlarged and leaky capillaries, which predispose… read more here.
Keywords: disease; ccm; stress; altered redox ... See more keywords