Human Huntington's Disease iPSC-Derived Cortical Neurons Display Altered Transcriptomics, Morphology, and Maturation.
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DOI: 10.1016/j.celrep.2018.09.076
Abstract: Huntington's disease (HD) is a neurodegenerative disease caused by an expanded CAG repeat in the Huntingtin (HTT) gene. Induced pluripotent stem cell (iPSC) models of HD provide an opportunity to study the mechanisms underlying disease… read more here.
Keywords: huntington disease; disease; altered transcriptomics; display altered ... See more keywords