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Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-42173-2
Abstract: Swainsonine (SW) is a toxic alkaloid biosynthesized by the endophytic fungus Alternaria oxytropis in Oxytropis glabra. The biosynthetic pathway of SW is poorly understood. Saccharopine reductase/dehydrogenase of fungus plays an important role in this pathway.…
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Keywords:
biosynthesis;
reductase;
carboxylate reductase;
alternaria oxytropis ... See more keywords
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Published in 2021 at "Journal of Fungi"
DOI: 10.3390/jof7070538
Abstract: The legume Oxytropis sericea hosts a fungal endophyte, Alternaria oxytropis, which produces secondary metabolites (SM), including the toxin swainsonine. Polyketide synthase (PKS) and non-ribosomal peptide synthase (NRPS) enzymes are associated with biosynthesis of fungal SM.…
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Keywords:
pks nrps;
synthase;
endophyte alternaria;
alternaria oxytropis ... See more keywords