Synthesis of para- and meta-imino- or -amino-methyl pyridyl-appended p-tert-butyl-calix[4]arene or p-tert-butyl-thiacalix[4]arene in 1,3-alternate conformation
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DOI: 10.1039/c7nj01389b
Abstract: Herein, the multistep synthesis of eight new ligands based on either calix[4]arene or thiacalix[4]arene backbone blocked in a 1,3-alternate conformation was achieved. Both types of backbones were functionalized with pyridyl coordinating units using either imino… read more here.
Keywords: calix arene; tert butyl; arene; alternate conformation ... See more keywords
An alternate conformation of HCV E2 neutralizing face as an additional vaccine target
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DOI: 10.1126/sciadv.abb5642
Abstract: An alternate conformation is found for the major antibody target on hepatitis C virus to aid in rational vaccine design. To achieve global elimination of hepatitis C virus (HCV), an effective cross-genotype vaccine is needed.… read more here.
Keywords: hcv; target; neutralizing face; conformation ... See more keywords