Oxidative damage within alternative DNA structures results in aberrant mutagenic processing
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DOI: 10.1093/nar/gkaf066
Abstract: Abstract Genetic instability is a hallmark of cancer, and mutation hotspots in human cancer genomes co-localize with alternative DNA structure-forming sequences (e.g. H-DNA), implicating them in cancer etiology. H-DNA has been shown to stimulate genetic… read more here.
Keywords: oxidative damage; alternative dna; dna; genetic instability ... See more keywords