In silico methods for co-transcriptional RNA secondary structure prediction and for investigating alternative RNA structure expression.
Sign Up to like & getrecommendations! Published in 2017 at "Methods"
DOI: 10.1016/j.ymeth.2017.04.009
Abstract: RNA transcripts are the primary products of active genes in any living organism, including many viruses. Their cellular destiny not only depends on primary sequence signals, but can also be determined by RNA structure. Recent… read more here.
Keywords: structure expression; alternative rna; rna; structure ... See more keywords
DNA-catalysed alternative RNA splicing.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc00812b
Abstract: We report DNA-catalysed alternative RNA splicing in vitro. Using modular DNA catalysts with RNA endonuclease and RNA ligase activities, we show that DNA can modulate RNA structure and activity. Furthermore, we illustrate that such DNA-catalysed… read more here.
Keywords: dna; rna splicing; dna catalysed; alternative rna ... See more keywords
Alternative RNA Splicing in the Retina: Insights and Perspectives.
Sign Up to like & getrecommendations! Published in 2023 at "Cold Spring Harbor perspectives in medicine"
DOI: 10.1101/cshperspect.a041313
Abstract: Alternative splicing is a fundamental and highly regulated post-transcriptional process that enhances transcriptome and proteome diversity. This process is particularly important in neuronal tissues, such as the retina, which exhibit some of the highest levels… read more here.
Keywords: rna splicing; alternative rna; splicing retina; alternative splicing ... See more keywords
Abnormal global alternative RNA splicing in COVID-19 patients
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Genetics"
DOI: 10.1371/journal.pgen.1010137
Abstract: Viral infections can alter host transcriptomes by manipulating host splicing machinery. Despite intensive transcriptomic studies on SARS-CoV-2, a systematic analysis of alternative splicing (AS) in severe COVID-19 patients remains largely elusive. Here we integrated proteomic… read more here.
Keywords: abnormal global; covid patients; rna splicing; alternative rna ... See more keywords
Alternative RNA Splicing in Fatty Liver Disease
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2021.613213
Abstract: Alternative RNA splicing is a process by which introns are removed and exons are assembled to construct different RNA transcript isoforms from a single pre-mRNA. Previous studies have demonstrated an association between dysregulation of RNA… read more here.
Keywords: fatty liver; alternative rna; rna; disease ... See more keywords
Alternative RNA Splicing Expands the Developmental Plasticity of Flowering Transition
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2019.00606
Abstract: Precise control of the developmental phase transitions, which ranges from seed germination to flowering induction and senescence, is essential for propagation and reproductive success in plants. Flowering induction represents the vegetative-to-reproductive phase transition. An extensive… read more here.
Keywords: transition; alternative rna; developmental plasticity; flowering transition ... See more keywords
Alternative RNA Conformations: Companion or Combatant
Sign Up to like & getrecommendations! Published in 2022 at "Genes"
DOI: 10.3390/genes13111930
Abstract: RNA molecules, in one form or another, are involved in almost all aspects of cell physiology, as well as in disease development. The diversity of the functional roles of RNA comes from its intrinsic ability… read more here.
Keywords: companion combatant; rna molecules; rna; conformations companion ... See more keywords