Translational derepression of Elavl4 isoforms at their alternative 5′ UTRs determines neuronal development
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-15412-8
Abstract: Neurodevelopment requires precise regulation of gene expression, including post-transcriptional regulatory events such as alternative splicing and mRNA translation. However, translational regulation of specific isoforms during neurodevelopment and the mechanisms behind it remain unknown. Using RNA-seq… read more here.
Keywords: post transcriptional; alternative utrs; neuronal development; translation ... See more keywords
Alternative 3′ UTRs direct localization of functionally diverse protein isoforms in neuronal compartments
Sign Up to like & getrecommendations! Published in 2019 at "Nucleic Acids Research"
DOI: 10.1093/nar/gky1270
Abstract: The proper subcellular localization of RNAs and local translational regulation is crucial in highly compartmentalized cells, such as neurons. RNA localization is mediated by specific cis-regulatory elements usually found in mRNA 3'UTRs. Therefore, processes that… read more here.
Keywords: protein isoforms; alternative utrs; localization functionally; functionally diverse ... See more keywords
Alternative 3'-untranslated regions regulate high salt tolerance of Spartina alterniflora.
Sign Up to like & getrecommendations! Published in 2023 at "Plant physiology"
DOI: 10.1093/plphys/kiad030
Abstract: High salt stress continues to challenge the growth and survival of many plants. Alternative polyadenylation (APA) produces mRNAs with different 3'-untranslated regions (3' UTRs) to regulate gene expression at the post-transcriptional level. However, the roles… read more here.
Keywords: untranslated regions; high salt; alternative utrs; salt stress ... See more keywords