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Copper-Free Alternatives to Access Ketone Building Blocks from Grignard Reagents

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Published in 2022 at "ACS Omega"

DOI: 10.1021/acsomega.1c06202

Abstract: Grignard reactions are an efficient way to form carbon–carbon bonds with widespread applications in large-scale processes. Classically, the electrophiles of choice to form ketones from Grignard reagents are acid chlorides. The reactions are typically catalyzed… read more here.

Keywords: grignard reagents; alternatives access; copper free; free alternatives ... See more keywords