Oncogenic G12D mutation alters local conformations and dynamics of K-Ras
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DOI: 10.1038/s41598-019-48029-z
Abstract: K-Ras is the most frequently mutated oncoprotein in human cancers, and G12D is its most prevalent mutation. To understand how G12D mutation impacts K-Ras function, we need to understand how it alters the regulation of… read more here.
Keywords: mutation alters; local conformations; oncogenic g12d; g12d mutation ... See more keywords