Loss of Insulin/IGF-1 Receptors in Muscle Coordinately Downregulates Mitochondrial Metabolism and Alters Mitophagy via Foxo Transcription Factors
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DOI: 10.2337/db18-187-or
Abstract: Diabetes is associated with decreased muscle strength and energy production. There is a strong association between muscle insulin resistance and mitochondrial abnormalities, but cause/effect remains hotly debated. Recently, we showed that insulin receptor (IR) and… read more here.
Keywords: insulin; metabolism; muscle; alters mitophagy ... See more keywords