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   Articles with "altitude pulmonary" as a keyword



High altitude pulmonary edema in children: A systematic review

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recommendations! Published in 2022 at "Pediatric Pulmonology"

DOI: 10.1002/ppul.26294

Abstract: High altitude pulmonary edema (HAPE) is a form of acute noncardiogenic pulmonary edema caused by altitude‐related hypoxia seen in children as well as in adults. In this systematic review we focus in HAPE occurring in… read more here.

Keywords: edema; systematic review; high altitude; pulmonary edema ... See more keywords

Pediatric high‐altitude pulmonary edema and acute mountain sickness: Clinical features and risk determinants

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recommendations! Published in 2024 at "Pediatric Pulmonology"

DOI: 10.1002/ppul.27101

Abstract: This investigation aimed to delineate the clinical manifestations associated with high‐altitude pulmonary edema (HAPE) and acute mountain sickness (AMS) in pediatric populations and find the risk factors of HAPE. read more here.

Keywords: high altitude; acute mountain; pulmonary edema; mountain sickness ... See more keywords

Chinese medicinal plants for the potential management of high-altitude pulmonary oedema and pulmonary hypertension

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recommendations! Published in 2020 at "Pharmaceutical Biology"

DOI: 10.1080/13880209.2020.1804407

Abstract: Abstract Context Despite the abundance of knowledge regarding high-altitude pulmonary edoema (HAPE) and high-altitude pulmonary hypertension (HAPH), their prevalence continues to be on the rise. Thus, there is an urgent need for newer safe, effective,… read more here.

Keywords: pulmonary hypertension; altitude pulmonary; medicinal plants; high altitude ... See more keywords
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Swine-influenza (H1N1 influenza) mimicking a case of high altitude pulmonary oedema (HAPO)

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recommendations! Published in 2020 at "BMJ Case Reports"

DOI: 10.1136/bcr-2019-232564

Abstract: Here we present a case of a 37-year-old soldier of Indian Army, posted in high altitude area of Ladakh region (>4200 m), who after rejoining after a month leave, presented with dry cough, low-grade fever… read more here.

Keywords: influenza; case; h1n1 influenza; high altitude ... See more keywords
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Exploring new heights with pulmonary functional imaging: insights into high-altitude pulmonary edema.

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recommendations! Published in 2017 at "Journal of applied physiology"

DOI: 10.1152/japplphysiol.00168.2017

Abstract: the unique environmental challenge to the pulmonary physiology from exposure to high altitudes may hold unique insights into regulation of pulmonary function under stress. For example, high-altitude pulmonary edema (HAPE) is a mysterious disease characterized… read more here.

Keywords: exploring new; physiology; pulmonary edema; high altitude ... See more keywords

Analysis and Validation of the Network Pharmacology of the Mechanism of Glycyrrhetinic Acid for the Treatment of High-Altitude Pulmonary Hypertension

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recommendations! Published in 2024 at "Journal of Food Biochemistry"

DOI: 10.1155/2024/1552878

Abstract: Glycyrrhetinic acid (GA) is a pentacyclic triterpene component in Glycyrrhize glabra L, it has demonstrated an inhibitive effect on high-altitude pulmonary hypertension (HAPH), but the molecular action is still not known. We aimed to explore… read more here.

Keywords: high altitude; glycyrrhetinic acid; pharmacology; altitude pulmonary ... See more keywords
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A machine learning-based severity stratification tool for high altitude pulmonary edema

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recommendations! Published in 2025 at "BMC Medical Informatics and Decision Making"

DOI: 10.1186/s12911-025-02992-y

Abstract: This study aimed to identify key predictors for the severity of High Altitude Pulmonary Edema (HAPE) to assist clinicians in promptly recognizing severely affected patients in the emergency department, thereby reducing associated mortality rates. Multinomail… read more here.

Keywords: high altitude; pulmonary edema; severity; model ... See more keywords

PHPT1 acts as an inhibitor in high-altitude pulmonary hypertension via negative TRPV5 signaling regulation

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recommendations! Published in 2025 at "Journal of Translational Medicine"

DOI: 10.1186/s12967-025-06980-8

Abstract: Low barometric pressure hypoxia at high altitudes triggers vascular remodeling, resulting in high-altitude pulmonary hypertension (HAPH). The key step is the transformation of pulmonary artery smooth muscle cells (PASMCs) from a contractile to synthetic phenotype.… read more here.

Keywords: phpt1; high altitude; altitude pulmonary; pulmonary hypertension ... See more keywords

High Altitude Pulmonary Edema, High Altitude Cerebral Edema, and Acute Mountain Sickness: an enhanced opinion from the High Andes – La Paz, Bolivia 3,500 m

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recommendations! Published in 2022 at "Reviews on Environmental Health"

DOI: 10.1515/reveh-2021-0172

Abstract: Abstract Traveling to high altitudes for entertainment or work is sometimes associated with acute high altitude pathologies. In the past, scientific literature from the lowlander point of view was primarily based on mountain climbing. Sea… read more here.

Keywords: mountain sickness; acute mountain; high altitude; altitude ... See more keywords

Bioactive compound combinations from Rhodiola tangutica alleviate pulmonary vascular remodeling in high-altitude pulmonary hypertension rats through the PI3K–AKT pathway

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recommendations! Published in 2025 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2025.1582677

Abstract: Background Hypoxia-induced pulmonary vascular remodeling is central to the development of high-altitude pulmonary hypertension (HAPH). Rhodiola tangutica has traditionally been used to prevent chronic mountain sickness. Although its active fraction (ACRT) shows therapeutic potential for… read more here.

Keywords: pulmonary vascular; vascular remodeling; high altitude; hypoxia ... See more keywords

Initial Treatment of High-Altitude Pulmonary Edema: Comparison of Oxygen and Auto-PEEP

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recommendations! Published in 2022 at "International Journal of Environmental Research and Public Health"

DOI: 10.3390/ijerph192316185

Abstract: Background: Improvement of oxygenation is the aim in the therapy of high-altitude pulmonary edema (HAPE). However, descent is often difficult and hyperbaric chambers, as well as bottled oxygen, are often not available. We compare Auto-PEEP… read more here.

Keywords: auto peep; auto; high altitude; pulmonary edema ... See more keywords