Altered DNA repair creates novel Alu/Alu repeat‐mediated deletions
Sign Up to like & getrecommendations! Published in 2021 at "Human Mutation"
DOI: 10.1002/humu.24193
Abstract: Alu elements are the most abundant source of nonallelic homology that influences genetic instability in the human genome. When there is a DNA double‐stranded break, the Alu element's high copy number, moderate length and distance… read more here.
Keywords: dna repair; dna; repeat mediated; alu alu ... See more keywords
ALUternative Regulation for Gene Expression.
Sign Up to like & getrecommendations! Published in 2017 at "Trends in cell biology"
DOI: 10.1016/j.tcb.2017.01.002
Abstract: Alu elements belong to the primate-specific SINE family of retrotransposons and constitute almost 11% of the human genome. Alus are transcribed by RNA polymerase (Pol) III and are inserted back into the genome with the… read more here.
Keywords: gene; aluternative regulation; alu elements; gene expression ... See more keywords