Pulmonary alveolar regeneration in adult COVID-19 patients
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DOI: 10.1038/s41422-020-0369-7
Abstract: Dear Editor, Alveolar regeneration after an acute lung injury has been observed in many mammals. Results in animal models have shown that alveolar type II (AT2) cells function as resident alveolar stem cells that can… read more here.
Keywords: alveolar regeneration; at2 cells; at1 cells; at2 ... See more keywords
Telomere shortening impairs alveolar regeneration
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DOI: 10.1111/cpr.13211
Abstract: Short telomeres in alveolar type 2 (AT2) cells have been associated with many lung diseases. The study aimed to investigate the regeneration capacity of AT2 cells with short telomeres by knocking out Tert in mice… read more here.
Keywords: regeneration; telomere shortening; shortening impairs; impairs alveolar ... See more keywords
Contribution of Trp63CreERT2-labeled cells to alveolar regeneration is independent of tuft cells
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DOI: 10.7554/elife.78217
Abstract: Viral infection often causes severe damage to the lungs, leading to the appearance of ectopic basal cells (EBCs) and tuft cells in the lung parenchyma. Thus far, the roles of these ectopic epithelial cells in… read more here.
Keywords: cells alveolar; trp63creert2; alveolar regeneration; tuft ... See more keywords