Association of Acquired and Heritable Factors With Intergenerational Differences in Age at Symptomatic Onset of Alzheimer Disease Between Offspring and Parents With Dementia
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DOI: 10.1001/jamanetworkopen.2019.13491
Abstract: This cohort study examines the associations of acquired and heritable factors associated with intergenerational differences in age at symptomatic onset of Alzheimer disease among offspring of parents with Alzheimer disease. read more here.
Keywords: acquired heritable; heritable factors; alzheimer disease; differences age ... See more keywords
Association of Plasma Amylin Concentration With Alzheimer Disease and Brain Structure in Older Adults
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DOI: 10.1001/jamanetworkopen.2019.9826
Abstract: This cohort study uses data from second-generation participants in the Framingham Heart Study to analyze the association of plasma amylin concentration with Alzheimer disease risk and brain structure. read more here.
Keywords: amylin concentration; alzheimer disease; association plasma; concentration alzheimer ... See more keywords
Effect of Rotigotine vs Placebo on Cognitive Functions Among Patients With Mild to Moderate Alzheimer Disease
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DOI: 10.1001/jamanetworkopen.2020.10372
Abstract: This randomized clinical trial evaluates whether treatment with the dopaminergic agonist rotigotine has an effect on cognitive function in patients with mild to moderate Alzheimer disease in Italy. read more here.
Keywords: alzheimer disease; rotigotine; moderate alzheimer; effect ... See more keywords
Knowledge and Attitudes Concerning Aducanumab Among Older Americans After FDA Approval for Treatment of Alzheimer Disease
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DOI: 10.1001/jamanetworkopen.2021.48355
Abstract: This survey study examines the understanding of aducanumab and attitudes toward its potential outcomes among older Americans after the drug's approval by the US Food and Drug Administration (FDA) for the treatment for Alzheimer disease. read more here.
Keywords: among older; approval; alzheimer disease; treatment alzheimer ... See more keywords
Association of Alzheimer Disease With Life Expectancy in People With Down Syndrome
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DOI: 10.1001/jamanetworkopen.2022.12910
Abstract: This meta-analysis assesses whether the variability in symptom onset of Alzheimer disease in Down syndrome is similar to autosomal dominant Alzheimer disease and its association with mortality. read more here.
Keywords: disease; alzheimer disease; disease life; association alzheimer ... See more keywords
Longitudinal Clinical and Cognitive Changes Along the Alzheimer Disease Continuum in Down Syndrome
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DOI: 10.1001/jamanetworkopen.2022.25573
Abstract: Key Points Question Are age, intellectual disability (ID), and clinical status associated with Alzheimer disease (AD) progression and longitudinal cognitive decline in adults with Down syndrome (DS)? Findings In this cohort study of 632 adults… read more here.
Keywords: cognitive changes; clinical cognitive; changes along; disease ... See more keywords
Consumer Assessment of Healthcare Providers and Systems Among Racial and Ethnic Minority Patients With Alzheimer Disease and Related Dementias
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DOI: 10.1001/jamanetworkopen.2022.33436
Abstract: This cross-sectional study evaluates racial and ethnic disparities in Consumer Assessement of Healthcare Providers and Systems measures among patients with Alzheimer Disease and related dementias. read more here.
Keywords: healthcare providers; disease related; alzheimer disease; racial ethnic ... See more keywords
Blood Leukocyte Counts in Alzheimer Disease
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DOI: 10.1001/jamanetworkopen.2022.35648
Abstract: Key Points Question What is the relevance of types of blood leukocytes in Alzheimer disease (AD)? Findings In this cohort study of 101 582 individuals in the Danish general population, low baseline blood monocyte counts were… read more here.
Keywords: increased risk; blood leukocyte; alzheimer disease; monocyte counts ... See more keywords
Transferability of Alzheimer Disease Polygenic Risk Score Across Populations and Its Association With Alzheimer Disease-Related Phenotypes
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DOI: 10.1001/jamanetworkopen.2022.47162
Abstract: Key Points Question Is a polygenic risk score (PRS) derived from European ancestry data associated with Alzheimer disease (AD) dementia risk in non-European populations? Findings In this cohort study of genome data from European and… read more here.
Keywords: disease; alzheimer disease; risk score; polygenic risk ... See more keywords
Association of Genetic Variants Linked to Late-Onset Alzheimer Disease With Cognitive Test Performance by Midlife
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DOI: 10.1001/jamanetworkopen.2022.5491
Abstract: Key Points Question At what age do individuals with higher genetic risk of Alzheimer disease first show cognitive differences from individuals with lower genetic risk, and which of 32 cognitive measures show the earliest difference?… read more here.
Keywords: alzheimer; alzheimer disease; higher genetic; genetic risk ... See more keywords
Risk of Discharge to Lower-Quality Nursing Homes Among Hospitalized Older Adults With Alzheimer Disease and Related Dementias
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DOI: 10.1001/jamanetworkopen.2022.55134
Abstract: Key Points Question Are hospitalized older adults with Alzheimer disease and related dementias (ADRD) more likely to be discharged to lower-quality skilled nursing facilities (SNFs)? Findings In this cross-sectional analysis of more than 2 million… read more here.
Keywords: lower quality; quality; older adults; hospitalized older ... See more keywords