Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer’s and Pick’s diseases
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DOI: 10.7554/elife.43584
Abstract: Assembly of microtubule-associated protein tau into filamentous inclusions underlies a range of neurodegenerative diseases. Tau filaments adopt different conformations in Alzheimer’s and Pick’s diseases. Here, we used cryo- and immuno- electron microscopy to characterise filaments… read more here.
Keywords: induced tau; alzheimer pick; heparin induced; pick diseases ... See more keywords