Breathing new life into the rational design of Alzheimer’s therapeutics
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DOI: 10.1016/j.cell.2020.12.036
Abstract: γ-secretase is a promising therapeutic target for Alzheimer's disease, but all inhibitors and modulators have failed due to toxicity or low efficacy. In this issue of Cell, Yang et al. provide cryo-EM structures of γ-secretase bound to… read more here.
Keywords: new life; breathing new; design alzheimer; alzheimer therapeutics ... See more keywords