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Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.1c04652.s001
Abstract: A simple and economical process for producing amantadine hydrochloride (1) on a 250 g scale, an antiviral and anti-Parkinson drug, has been developed. Several methods for the preparation of 1 through intermediate N-(1-adamantyl)-acetamide (4) in…
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Keywords:
simple economical;
economical process;
process producing;
amantadine hydrochloride ... See more keywords