Ombuin ameliorates diabetic nephropathy in rats by anti‐inflammation and antifibrosis involving Notch 1 and PPAR γ signaling pathways
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DOI: 10.1002/ddr.21956
Abstract: Diabetic nephropathy (DN) is a common complication of diabetes and it is urgent to develop effective therapies for DN. In this study, high‐sucrose and high‐fat diet combined with streptozotocin was used to induce DN in… read more here.
Keywords: inflammation; ppar; ombuin ameliorates; ameliorates diabetic ... See more keywords
Hyperoside ameliorates diabetic nephropathy induced by STZ via targeting the miR-499-5p/APC axis.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of pharmacological sciences"
DOI: 10.1016/j.jphs.2021.02.005
Abstract: Diabetic nephropathy is a serious complication of diabetes. Hyperoside has been widely reported to ameliorate diabetes-associated disease. The current study is designed to explore the mechanism of hyperoside in diabetic nephropathy. In the present study,… read more here.
Keywords: hyperoside ameliorates; apc; ameliorates diabetic; diabetic nephropathy ... See more keywords
Relaxin-3 Ameliorates Diabetic Cardiomyopathy by Inhibiting Endoplasmic Reticulum Stress
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DOI: 10.1155/2022/9380283
Abstract: Background This study is aimed at investigating whether relaxin-3 exhibits protective effects against cardiomyopathy in diabetic rats by suppressing ERS. Methods Eighty male SD rats were randomly divided into two groups: controls (n = 20)… read more here.
Keywords: relaxin; relaxin ameliorates; cardiomyopathy inhibiting; ameliorates diabetic ... See more keywords