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AMPA Receptor Antagonist Perampanel Ameliorates Post-Stroke Functional and Cognitive Impairments

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Published in 2018 at "Neuroscience"

DOI: 10.1016/j.neuroscience.2018.06.043

Abstract: Perampanel (PER), a noncompetitive α-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor antagonist, clinically used for seizure control, has been reported to exert neuroprotective effects in experimental models of neurodegenerative diseases. However, few studies have investigated the therapeutic effects of… read more here.

Keywords: post stroke; receptor antagonist; cognitive impairments; infarct volumes ... See more keywords