Amelioration of amyloid-β-induced deficits by DcR3 in an Alzheimer’s disease model
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DOI: 10.1186/s13024-017-0173-0
Abstract: BackgroundMicroglia mediate amyloid-beta peptide (Aβ)-induced neuroinflammation, which is one of the key events in the pathogenesis of Alzheimer’s disease (AD). Decoy receptor 3 (DcR3)/TNFRSF6B is a pleiotropic immunomodulator that promotes macrophage differentiation toward the M2… read more here.
Keywords: amelioration amyloid; alzheimer disease; app; dcr3 ... See more keywords