Articles with "ameloblastoma" as a keyword



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Discovery of novel molecular characteristics and cellular biological properties in ameloblastoma

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Published in 2020 at "Cancer Medicine"

DOI: 10.1002/cam4.2931

Abstract: Ameloblastoma is a rare odontogenic benign tumor accounting for less than 1% of head and neck tumors. Advanced next generation sequencing (NGS) analyses identified high frequency of BRAF V600E and SMO L412F mutations in ameloblastoma.… read more here.

Keywords: medicine; kras responsive; ameloblastoma cells; ameloblastoma ... See more keywords
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BRAF V600E and previously unidentified KRAS G12C mutations in odontogenic tumors may affect MAPK activation differently depending on tumor type

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Published in 2022 at "Genes"

DOI: 10.1002/gcc.23040

Abstract: Although several types of odontogenic tumors share the same mutations in MAPK pathway genes, their effects on MAPK activation remain unclarified. This study aimed to evaluate the associations between these mutations and ERK phosphorylation in… read more here.

Keywords: braf v600e; previously unidentified; ameloblastoma; mapk activation ... See more keywords
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Yes-associated protein (YAP) molecule expression in odontogenic epithelium of ameloblastoma

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Published in 2018 at "Clinical Oral Investigations"

DOI: 10.1007/s00784-018-2693-6

Abstract: ObjectivesYAP (Yes-associated protein molecule) augments multiple processes known to be important for tumor progression and metastasis. Hence, the application of YAP as a targeted therapy for several malignancies has been documented in the literature. Ameloblastoma… read more here.

Keywords: expression odontogenic; dental follicle; ameloblastoma; expression ... See more keywords
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Intercellular signaling between ameloblastoma and osteoblasts

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Published in 2022 at "Biochemistry and Biophysics Reports"

DOI: 10.1016/j.bbrep.2022.101233

Abstract: Ameloblastoma is an odontogenic tumor located in the bone jaw with clinical characteristics of extensive bone resorption. It is a locally invasive tumor with a high recurrence rate despite adequate surgical removal. In bone disease,… read more here.

Keywords: conditioned medium; ameloblastoma cells; mc3t3 cells; ameloblastoma ... See more keywords
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Desmoplastic ameloblastoma: a systematic review of the cases reported in the literature.

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Published in 2019 at "International journal of oral and maxillofacial surgery"

DOI: 10.1016/j.ijom.2019.11.004

Abstract: The aim of this study was to integrate the available data published on desmoplastic ameloblastoma (DA) into a comprehensive analysis of its clinical/radiographic features. As it is not clear whether the hybrid ameloblastoma has a… read more here.

Keywords: location; clinical radiographic; desmoplastic ameloblastoma; non hybrid ... See more keywords
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Ameloblastoma of the Jaw in Three Species of Rodent: a Domestic Brown Rat (Rattus norvegicus), Syrian Hamster (Mesocricetus auratus) and Amargosa Vole (Microtus californicus scirpensis).

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Published in 2017 at "Journal of comparative pathology"

DOI: 10.1016/j.jcpa.2017.07.002

Abstract: Ameloblastoma is a locally aggressive tumour derived from the odontogenic epithelium of the developing tooth germ. This uncommon odontogenic tumour is generally considered benign, but rarely, both distant metastasis and cytological atypia occur and this… read more here.

Keywords: vole microtus; rattus norvegicus; rat rattus; hamster ... See more keywords
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Upregulation of eukaryotic translation initiation factor 3 subunit a promotes cell survival in ameloblastoma.

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Published in 2019 at "Oral surgery, oral medicine, oral pathology and oral radiology"

DOI: 10.1016/j.oooo.2019.02.016

Abstract: OBJECTIVES This study aimed to detect the expression of eukaryotic translation initiation factor 3 subunit a (eIF3a) in ameloblastoma (AB) tissues compared with normal oral mucosa (NOM) tissues and investigate the roles of eIF3a in… read more here.

Keywords: eukaryotic translation; ameloblastoma; translation initiation; factor subunit ... See more keywords
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SYNCHRONOUS EXPRESSION OF E-CADHERIN AND SYNDECAN-1 IN AMELOBLASTOMA: A PRELIMINARY STUDY

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Published in 2019 at "Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology"

DOI: 10.1016/j.oooo.2019.02.173

Abstract: Objectives This study aimed to evaluate the percentage of expression and the possibility of synchronicity between E-cadherin (Ecad) and Epithelial syndecan-1 (Syn-1E) in Unicystic ameloblastoma (UAM) and solid multicystic ameloblastoma (SMA) and the association between… read more here.

Keywords: expression; ameloblastoma; synchronous expression; synchronicity ... See more keywords
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CORRELATION OF SYNDECAN 1 EXPRESSION IN SOLID AND UNICYSTIC AMELOBLASTOMA AND ITS CELLULAR COMPONENTS

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Published in 2021 at "Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology"

DOI: 10.1016/j.oooo.2021.03.162

Abstract: Background Syndecan-1 (SDC1) is a transmembrane heparan sulfate proteoglycan (also known as CD138), participates in odontogenesis, and is known to regulate cytoskeletal organization, growth factor signaling, cell–cell adhesion, and extracellular matrix attachment. Loss of expression… read more here.

Keywords: ameloblastoma; cellular components; syndecan expression; solid unicystic ... See more keywords
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Maxillary unicystic ameloblastoma in a 6-week-old filly evaluated with computed tomography.

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Published in 2017 at "Australian veterinary journal"

DOI: 10.1111/avj.12610

Abstract: CASE REPORT A 6-week-old Thoroughbred filly was presented for evaluation of an expansile mass overlying the right nasal passage and causing respiratory stertor. On skull radiographs, there was a loculated, soft tissue-opaque mass identified dorsal… read more here.

Keywords: computed tomography; unicystic ameloblastoma; week old; mass ... See more keywords
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Ultra-frequent HRAS p.Q61R somatic mutation in canine acanthomatous ameloblastoma reveals pathogenic similarities with human ameloblastoma.

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Published in 2019 at "Veterinary and comparative oncology"

DOI: 10.1111/vco.12487

Abstract: Ameloblastoma is a locally aggressive odontogenic tumour that occurs in humans and dogs. Most ameloblastomas (AM) in humans harbour mutually-exclusive driving mutations in BRAF, HRAS, KRAS, NRAS or FGFR2 that activate MAPK signalling, and in… read more here.

Keywords: acanthomatous ameloblastoma; hras q61r; ameloblastoma; ultra frequent ... See more keywords