Controlling Enamel Remineralization by Amyloid-Like Amelogenin Mimics.
Sign Up to like & getrecommendations! Published in 2020 at "Advanced materials"
DOI: 10.1002/adma.202002080
Abstract: In situ regeneration of the enamel-like structure of hydroxyapatite (HAp) crystals under oral conditions is significant for dental caries treatment. However, it is still a challenge for dentists to duplicate the elegant and well-aligned apatite… read more here.
Keywords: amg; hap crystals; amelogenin; amyloid like ... See more keywords
Novel LRAP‐binding partner revealing the plasminogen activation system as a regulator of cementoblast differentiation and mineral nodule formation in vitro
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.29331
Abstract: Amelogenin isoforms, including full‐length amelogenin (AMEL) and leucine‐rich amelogenin peptide (LRAP), are major components of the enamel matrix, and are considered as signaling molecules in epithelial–mesenchymal interactions regulating tooth development and periodontal regeneration. Nevertheless, the… read more here.
Keywords: nodule formation; plasminogen; amelogenin; mineral nodule ... See more keywords
Minimal amelogenin domain for enamel formation.
Sign Up to like & getrecommendations! Published in 2021 at "JOM"
DOI: 10.1007/s11837-021-04687-x
Abstract: Amelogenin is the most abundant matrix protein guiding hydroxyapatite formation in enamel, the durable bioceramic tissue that covers vertebrate teeth. Here, we sought to refine structure-function for an amelogenin domain based on in vitro data… read more here.
Keywords: formation; amelogenin; amelogenin domain; function ... See more keywords
Sex estimation using sexually dimorphic amelogenin protein fragments in human enamel
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Archaeological Science"
DOI: 10.1016/j.jas.2018.08.011
Abstract: Abstract Amelogenin genes are located on both X and Y sex chromosomes in humans and are a major focus of DNA-based sex estimation methods. Amelogenin proteins, AMELX_HUMAN and AMELY_HUMAN, are expressed in the tooth organ… read more here.
Keywords: amelogenin; sexually dimorphic; sex estimation; sex ... See more keywords
Residue-Specific Insights into the Intermolecular Protein-Protein Interfaces Driving Amelogenin Self-Assembly in Solution.
Sign Up to like & getrecommendations! Published in 2022 at "Biochemistry"
DOI: 10.1021/acs.biochem.2c00522
Abstract: Amelogenin, the dominant organic component (>90%) in the early stages of amelogenesis, orchestrates the mineralization of apatite crystals into enamel. The self-association properties of amelogenin as a function of pH and protein concentration have been… read more here.
Keywords: protein protein; self assembly; amelogenin; protein interfaces ... See more keywords
Recombinant amelogenin peptide TRAP promoting remineralization of early enamel caries: An in vitro study
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2023.1076265
Abstract: Objective: To explore the regulatory effect of recombinant amelogenin peptide TRAP on the remineralization of early enamel carious lesions. Methods: Forty-eight bovine enamel blocks that prepared initial lesions in vitro were split at random into… read more here.
Keywords: peptide trap; studied peptide; amelogenin; remineralization ... See more keywords