Viral ribonucleotide reductase attenuates the anti-herpes activity of acyclovir in contrast to amenamevir.
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DOI: 10.1016/j.antiviral.2020.104829
Abstract: Amenamevir is a helicase-primase inhibitor of herpes simplex virus (HSV) and varicella-zoster virus (VZV) and is used for the treatment of herpes zoster in Japan. The half maximal effective concentrations (EC50s) of acyclovir and sorivudine… read more here.
Keywords: amenamevir; hsv; anti herpes; activity ... See more keywords