African-American Prostate Cancer Disparities
Sign Up to like & getrecommendations! Published in 2017 at "Current Urology Reports"
DOI: 10.1007/s11934-017-0724-5
Abstract: Purpose of ReviewThe purpose of this review is to examine prostate cancer racial disparities specific to the African-American population.Recent FindingsAfrican-American men are more likely to be diagnosed with prostate cancer, present at an earlier age;… read more here.
Keywords: cancer disparities; american prostate; prostate cancer; cancer ... See more keywords
A Novel FGFR3 Splice Variant Preferentially Expressed in African American Prostate Cancer Drives Aggressive Phenotypes and Docetaxel Resistance
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DOI: 10.1158/1541-7786.mcr-19-0415
Abstract: Alternative splicing (AS) has been shown to participate in prostate cancer development and progression; however, a link between AS and prostate cancer health disparities has been largely unexplored. Here we report on the cloning of… read more here.
Keywords: fgfr3; splice variant; cancer; american prostate ... See more keywords
Molecular Insight into Drug Resistance Mechanism Conferred by Aberrant PIK3CD Splice Variant in African American Prostate Cancer
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DOI: 10.3390/cancers15041337
Abstract: Simple Summary Higher incidence and mortality rates were observed in African American vs. European American prostate cancers. Alternative mRNA splicing has been suggested as an oncogenic driver in aggressive cancers as well as cancer disparities.… read more here.
Keywords: pi3k; prostate; african american; drug resistance ... See more keywords