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Efficacy and safety of the glycine transporter type-1 inhibitor AMG 747 for the treatment of negative symptoms associated with schizophrenia

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Published in 2017 at "Schizophrenia Research"

DOI: 10.1016/j.schres.2016.10.027

Abstract: OBJECTIVE To determine the safety and efficacy of AMG 747, an oral inhibitor of glycine transporter type-1 (GlyT1), as an add-on to antipsychotic therapy in clinically stable people with schizophrenia with enduring negative symptoms. METHOD… read more here.

Keywords: glycine transporter; negative symptoms; treatment; amg 747 ... See more keywords